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Carnivore Plague

Carnivore plague (infectious catarrhal fever) is an acute viral disease characterized by fever, catarrh of the mucous membranes, pneumonia, skin exanthema and damage to the nervous system

The causative agent of the disease is the RNA genomic virus, has immunosuppressive properties.

The plague virus is susceptible: the family of canids (dogs, raccoons, wolves, foxes), the family of marten (mink, sable) and other carnivorous animals. Animals of all ages are sick, but puppies of 2–5 months of age are most susceptible.

The source of infection is sick and ill animals, as well as animals in the incubation period. Virus carriage lasts 2-3 months in dogs, in fur animals – up to 6 months. The causative agent is excreted from the body with outflows from the nose and eyes, with coughing, sneezing, with saliva, urine and feces.

Symptoms
The incubation period is 2-14 days. The course is acute, acute, subacute, chronic, but can be atypical and abortive. Depending on the symptoms, the nervous, pulmonary, intestinal, mixed and skin forms of the disease are distinguished.

Pulmonary form
In the acute course, it is accompanied by an increase in body temperature to 39.5 ° C, which is maintained at that level for 10-15 days. The skin of the nose mirror is dry, cracks may appear. 1-2 days after the temperature rises, serous-mucous and then purulent outflows from the eyes appear, as a result of which the eyelids stick together, the eyes close. Rhinitis develops, and serous-purulent exudate is released from the nasal cavities, crusts form on the nasal speculum, the nostrils stick together, breathing becomes sniff, first a dry and then a wet cough appears.

Intestinal form
It is accompanied by the development of catarrh of the mucous membrane of the stomach and intestines, and is manifested by diarrhea. Feces are liquid, gray-yellow, and later brown. With hemorrhagic inflammation of the rectum, traces of blood are found in feces. In addition, there may be vomiting.

Nervous form
With the nervous form of the plague, animals experience excitement, convulsive contraction of the masticatory muscles and limbs, there may be paresis and paralysis of the hind limbs, epileptic seizures, and clonic and tetanic convulsions appear.

Treatment
Treatment should be comprehensive with the use of specific and symptomatic agents. The most effective specific agents at present are: avirocan (specific dog immunoglobulin against plague, hepatitis, coronavirus enteritis, and carnivorous parvovirus); immunoglobulin against parvovirus enteritis and carnivorous plague; medicinal globulin against plague, enteritis and hepatitis carnivores. Polyvalent serum against plague, parvovirus enteritis, and carnivorous viral hepatitis is somewhat less effective.

Recently, drugs belonging to the group of immunostimulants have become widespread: anandine, immunofan, cycloferon, cinoron, mixoferon, comedone, and ribotan. To suppress the secondary 38 bacterial microflora, antibacterial drugs with a prolonged action are used. After a course of antibiotic therapy, the use of probiotics is mandatory: lactobacterin, bifidumbacterin, bactisubtil, enterobifidin.

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